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Clinical trials have tested doses up to 2mg daily without safety concerns, but most women achieve optimal results at the 1mg dose level

The most common causes of this form of lower back pain include: Lumbar herniated disk

But specificity comes with a tradeoff: limited magnitude of effect, which we will examine when we get to the clinical data

Here's what the science actually says, where it came from, and what you should know before starting

The most frequently cited mechanistic findings come from a small group of obese-rodent studies published around the beginning of the 2000s